Serum Biomarker Chip Kit

High-Density Profiling

The Serum Biomarker Chip enables proteomics researchers to profile and pattern the molecular signature of human serum. The chip addresses the need for a high-throughput technology to enable research in the fields of risk stratification, disease prognosis, drug eligibility, prediction of safety and efficacy, and therapeutic monitoring.

The Serum Biomarker Chip is a single-capture antibody array built on the FAST Slide dual pad platform. Each slide has two identical arrays of antibodies printed in triplicate. Two-color fluorescent detection permits the researcher to reproducibly pattern the relative abundance of 120 human serum proteins between two samples, such as serum samples from diseased and healthy individuals.

Fluorescent labeling is done with the ULS Biotin Single Color Labeling System, available separately. Two-Color Labeling is also available for customers who prefer to do hapten and label swapping experiments.  The chip can be scanned with any standard fluorescence scanner. A reusable Slide Holder is also needed, either FAST Frame for 4 slides or Chip Clip for 1 slide

The Serum Biomarker Chip Kit includes two arrayed 2 pad FAST Slides, two dual Incubation Chambers, 5 ml Whatman Protein Array Blocking Buffer, and 125 ml Whatman Protein Array Wash Buffer.